Genetics 2012

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Research from 18 May 2012

  • Ji, Y. N., Wang, Q., Lin, X. Q., and Suo, L. J. CYP1A1 MspI polymorphisms and lung cancer risk: An updated meta-analysis involving 20,209 subjects. Cytokine . 12-5-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22579698
  • Mutschler, J., Abbruzzese, E., von der, Goltz C., Dinter, C., Mobascher, A., Thiele, H., Diaz-Lacava, A., Dahmen, N., Gallinat, J., Majic, T., Petrovsky, N., Kornhuber, J., Thuerauf, N., Grunder, G., Brinkmeyer, J., Wienker, T., Wagner, M., Winterer, G., and Kiefer, F. Genetic Variation in the Neuropeptide Y Gene Promoter Is Associated with Increased Risk of Tobacco Smoking. European Addiction Research 18[5], 246-252. 15-5-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22584873
  • Shi, J., Chatterjee, N., Rotunno, M., Wang, Y., Pesatori, A. C., Consonni, D., Li, P., Wheeler, W., Broderick, P., Henrion, M., Eisen, T., Wang, Z., Chen, W., Dong, Q., Albanes, D., Thun, M., Spitz, M. R., Bertazzi, P. A., Caporaso, N. E., Chanock, S. J., Amos, C. I., Houlston, R. S., and Landi, M. T. Inherited Variation at Chromosome 12p13.33, Including RAD52, Influences the Risk of Squamous Cell Lung Carcinoma. Cancer Discov. 2[2], 131-139. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22585858

Research from 11 May 2012

Research from 04 May 2012

  • Fehringer, G., Liu, G., Pintilie, M., Sykes, J., Cheng, D., Liu, N., Chen, Z., Seymour, L., Der, S. D., Shepherd, F. A., Tsao, M. S., and Hung, R. Association of the 15q25 and 5p15 lung cancer susceptibility regions with gene expression in lung tumour tissue. Cancer Epidemiology, Biomarkers and Prevention . 26-4-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22539604
  • Kunigal, S., Ponnusamy, M. P., Momi, N., Batra, S. K., and Chellappan, S. P. Nicotine, IFN-gamma and retinoic acid mediated induction of MUC4 in pancreatic cancer requires E2F1 and STAT-1 transcription factors and utilize different signaling cascades. Mol.Cancer 11[1], 24. 26-4-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22537161
  • Liang, H., Zhang, J., Shao, C., Zhao, L., Xu, W., Sutherland, L. C., and Wang, K. Differential expression of RBM5, EGFR and KRAS mRNA and protein in non-small cell lung cancer tissues. Journal of Experimental and Clinical Cancer Research 31[1], 36. 26-4-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22537942
  • Munafo, M. R., Timofeeva, M. N., Morris, R. W., Prieto-Merino, D., Sattar, N., Brennan, P., Johnstone, E. C., Relton, C., Johnson, P. C., Walther, D., Whincup, P. H., Casas, J. P., Uhl, G. R., Vineis, P., Padmanabhan, S., Jefferis, B. J., Amuzu, A., Riboli, E., Upton, M. N., Aveyard, P., Ebrahim, S., Hingorani, A. D., Watt, G., Palmer, T. M., Timpson, N. J., and Davey, Smith G. Association Between Genetic Variants on Chromosome 15q25 Locus and Objective Measures of Tobacco Exposure. Journal of the National Cancer Institute . 25-4-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22534784
  • Ware, J. J., van den Bree, M., and Munafo, M. R. From Men to Mice: CHRNA5/CHRNA3, Smoking Behavior and Disease. Nicotine Tob.Res.  27-4-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22544838

Research from 27 April 2012

  • Breitling, L. P., Salzmann, K., Rothenbacher, D., Burwinkel, B., and Brenner, H. Smoking, F2RL3 methylation, and prognosis in stable coronary heart disease. European Heart Journal . 17-4-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22511653
  • Chen, Y., Dawes, P. T., Packham, J. C., and Mattey, D. L. Interaction between smoking and functional polymorphism in the TGFB1 gene is associated with ischaemic heart disease and myocardial infarction in patients with rheumatoid arthritis: a cross-sectional study. Arthritis Res.Ther. 14[2], R81. 18-4-2012.  Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22513132
  • Domino, E. F., Evans, C. L., Ni, L., Guthrie, S. K., Koeppe, R. A., and Zubieta, J. K. Tobacco smoking produces greater striatal dopamine release in G-allele carriers with mu opioid receptor A118G polymorphism. Progress in Neuro-Psychopharmacology and Biological Psychiatry . 10-4-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22516252
  • Tsuang, M. T., Francis, T., Minor, K., Thomas, A., and Stone, W. S. Genetics of smoking and depression. Human Genetics . 17-4-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22526528

Research from 20 April 2012

  • Liu, Y., Wang, H., Lin, T., Wei, Q., Zhi, Y., Yuan, F., Song, B., Yang, J., and Chen, Z. Interactions between cigarette smoking and XPC-PAT genetic polymorphism enhance bladder cancer risk. Oncology Reports . 9-4-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22505326
  • Marteau, T. M., Aveyard, P., Munafo, M. R., Prevost, A. T., Hollands, G. J., Armstrong, D., Sutton, S., Hill, C., Johnstone, E., and Kinmonth, A. L. Effect on adherence to nicotine replacement therapy of informing smokers their dose is determined by their genotype: a randomised controlled trial. PLoS.One. 7[4], e35249. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22509402
  • Togashi, Y., Masago, K., Kubo, T., Fujimoto, D., Sakamori, Y., Nagai, H., Kim, Y. H., Togashi, K., and Mishima, M. Association between vascular-poor area of primary tumors and epidermal growth factor receptor gene status in advanced lung adenocarcinoma. Medical Oncology . 11-4-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22492281
  • Wan, E. S., Qiu, W., Baccarelli, A., Carey, V. J., Bacherman, H., Rennard, S. I., Agusti, A., Anderson, W., Lomas, D. A., and Demeo, D. L. Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome. Human Molecular Genetics . 6-4-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22492999

Research from 13 April 2012

  • Kossenkov, A. V., Dawany, N., Evans, T. L., Kucharczuk, J. C., Albelda, S. M., Showe, L. C., Showe, M. K., and Vachani, A. Peripheral immune cell gene expression predicts survival of patients with non-small cell lung cancer. PLoS.One. 7[3], e34392. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22479623

Research from 05 April 2012

  • Cardini, S., Dalli, J., Fineschi, S., Perretti, M., Lungarella, G., and Lucattelli, M. Genetic Ablation of the Fpr1 Gene Confers Protection from Smoking-Induced Lung Emphysema in Mice. American Journal of Respiratory Cell and Molecular Biology . 29-3-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22461430
  • Gallego, X., Ruiz-Medina, J., Valverde, O., Molas, S., Robles, N., Sabria, J., Crabbe, J. C., and Dierssen, M. Transgenic over expression of nicotinic receptor alpha 5, alpha 3, and beta 4 subunit genes reduces ethanol intake in mice. Alcohol . 27-3-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22459873

Research from 30 March 2012

  • Bloom, A. J., Harari, O., Martinez, M., Madden, P. A., Martin, N. G., Montgomery, G. W., Rice, J. P., Murphy, S. E., Bierut, L. J., and Goate, A. Use of a Predictive Model Derived from In Vivo Endophenotype Measurements to Demonstrate Associations with a Complex Locus, CYP2A6. Human Molecular Genetics . 26-3-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22451501
  • Kapoor, M., Wang, J. C., Bertelsen, S., Bucholz, K., Budde, J. P., Hinrichs, A., Agrawal, A., Brooks, A., Chorlian, D., Dick, D., Hesselbrock, V., Foroud, T., Kramer, J., Kuperman, S., Manz, N., Nurnberger, J., Jr., Porjesz, B., Rice, J., Tischfield, J., Xuei, X., Schuckit, M., Edenberg, H. J., Bierut, L. J., and Goate, A. M. Variants Located Upstream of CHRNB4 on Chromosome 15q25.1 Are Associated with Age at Onset of Daily Smoking and Habitual Smoking. PLoS.One. 7[3], e33513. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22438940
  • Kaur-Knudsen, D., Nordestgaard, B. G., and Bojesen, S. E. CHRNA3 genotype, nicotine dependence, lung function and disease in the general population. Eur.Respir.J.  22-3-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22441734
  • Marczylo, E. L., Amoako, A. A., Konje, J. C., Gant, T. W., and Marczylo, T. H. Smoking induces differential miRNA expression in human spermatozoa: A potential transgenerational epigenetic concern? Epigenetics. 7[5]. 1-5-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22441141

Research from 23 March 2012

  • Ito, H., McKay, J. D., Hosono, S., Hida, T., Yatabe, Y., Mitsudomi, T., Brennan, P., Tanaka, H., and Matsuo, K. Association between a Genome-Wide Association Study-Identified Locus and the Risk of Lung Cancer in Japanese Population. J.Thorac.Oncol.  16-3-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22430809
  • Langevin, S. M., Koestler, D. C., Christensen, B. C., Butler, R. A., Wiencke, J. K., Nelson, H. H., Houseman, E. A., Marsit, C. J., and Kelsey, K. T. Peripheral blood DNA methylation profiles are indicative of head and neck squamous cell carcinoma: An epigenome-wide association study. Epigenetics. 7[3], 291-299. 1-3-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22430805
  • Philibert, R. A., Sears, R. A., Powers, L. S., Nash, E., Bair, T., Gerke, A. K., Hassan, I., Thomas, C. P., Gross, T. J., and Monick, M. M. Coordinated DNA methylation and gene expression changes in smoker alveolar macrophages: specific effects on VEGF receptor 1 expression. Journal of Leukocyte Biology . 16-3-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22427682

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Research from 16 March 2012

  • Choi, H., Kratz, J., Pham, P., Lee, S., Ray, R., Kwon, Y. W., Mao, J. H., Kang, H. C., Jablons, D., and Kim, I. J. Development of a rapid and practical mutation screening assay for human lung adenocarcinoma. International Journal of Oncology . 7-3-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22407457
  • Ehrlich, S., Walton, E., Roffman, J. L., Weiss, D., Puls, I., Doehler, N., Burghardt, R., Lehmkuhl, U., Hillemacher, T., Muschler, M., and Frieling, H. Smoking, But Not Malnutrition, Influences Promoter-Specific DNA Methylation of the Proopiomelanocortin Gene in Patients With and Without Anorexia Nervosa. Can.J.Psychiatry 57[3], 168-176. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22398003
  • Ge, J., Ding, Z., Song, Y., and Wang, F. Smoking Dose Modifies the Association between C242T Polymorphism and Prevalence of Metabolic Syndrome in a Chinese Population. PLoS.One. 7[3], e31926. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22396743
  • Ito, K., Yano, T., Morodomi, Y., Yoshida, T., Kohno, M., Haro, A., Shikada, Y., Okamoto, T., Maruyama, R., and Maehara, Y. Serum Antioxidant Capacity and Oxidative Injury to Pulmonary DNA in Never-smokers with Primary Lung Cancer. Anticancer Research 32[3], 1063-1067. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22399633
  • Shen, G. Q., Li, L., and Wang, Q. K. Genetic Variant R952Q in LRP8 is Associated with Increased Plasma Triglyceride Levels in Patients with Early-Onset CAD and MI. Annals of Human Genetics . 8-3-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22404453

Research from 09 March 2012

  • Bentley, A. R., Kritchevsky, S. B., Harris, T. B., Newman, A. B., Bauer, D. C., Meibohm, B., Clark, A. G., and Cassano, P. A. Genetic variation in antioxidant enzymes and lung function. Free Radical Biology and Medicine . 29-2-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22387199
  • Gold, A. B., Wileyto, E. P., Lori, A., Conti, D., Cubells, J. F., and Lerman, C. Pharmacogenetic Association of the Galanin Receptor (GALR1) SNP rs2717162 with Smoking Cessation. Neuropsychopharmacology . 29-2-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22373943
  • Hosgood, H. D., III, Wang, W. C., Hong, Y. C., Wang, J. C., Chen, K., Chang, I. S., Chen, C. J., Lu, D., Yin, Z., Wu, C., Zheng, W., Qian, B., Park, J. Y., Kim, Y. H., Chatterjee, N., Chen, Y., Chang, G. C., Hsiao, C. F., Yeager, M., Tsai, Y. H., Wei, H., Kim, Y. T., Wu, W., Zhao, Z., Chow, W. H., Zhu, X., Lo, Y. L., Sung, S. W., Chen, K. Y., Yuenger, J., Kim, J. H., Huang, L., Chen, Y. H., Gao, Y. T., Kim, J. H., Huang, M. S., Jung, T. H., Caporaso, N., Zhao, X., Huan, Z., Yu, D., Kim, C. H., Su, W. C., Shu, X. O., Kim, I. S., Bassig, B., Chen, Y. M., Cha, S. I., Tan, W., Chen, H., Yang, T. Y., Sung, J. S., Wang, C. L., Li, X., Park, K. H., Yu, C. J., Ryu, J. S., Xiang, Y., Hutchinson, A., Kim, J. S., Cai, Q., Landi, M. T., Lee, K. M., Hung, J. Y., Park, J. Y., Tucker, M., Lin, C. C., Ren, Y., Perng, R. P., Chen, C. Y., Jin, L., Chen, K. C., Li, Y. J., Chiu, Y. F., Tsai, F. Y., Yang, P. C., Fraumeni, J. F., Jr., Seow, A., Lin, D., Zhou, B., Chanock, S., Hsiung, C. A., Rothman, N., and Lan, Q. Genetic variant in TP63 on locus 3q28 is associated with risk of lung adenocarcinoma among never-smoking females in Asia. Human Genetics . 25-2-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22367405
  • Lessov-Schlaggar, C. N., Kristjansson, S. D., Bucholz, K. K., Heath, A. C., and Madden, P. A. Genetic Influences on Developmental Smoking Trajectories. Addiction . 2-3-2012.Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22385035
  • Orloff, M. S., Zhang, L., Bebek, G., and Eng, C. Integrative Genomic Analysis Reveals Extended Germline Homozygosity with Lung Cancer Risk in the PLCO Cohort. PLoS.One. 7[2], e31975. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22384118
  • Rotunno, M., Lam, T. K., Vogt, A., Bertazzi, P. A., Lubin, J. H., Caporaso, N. E., and Landi, M. T. GSTM1 and GSTT1 copy numbers and mRNA expression in lung cancer. Molecular Carcinogenesis . 5-3-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22392686

Research from 24 February 2012

  • Julie, B. V., Petr, B., Lenka, S., Lenka, S., Zlata, P., Martin, F., Zbynek, S., Filip, Z., and Anna, V. Variability in CNR1 locus influences protein intake and smoking status in the Central-European population. Nutr.Neurosci.  2-2-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22334331

Research from 17 February 2012

  • Guo, N. L. and Wan, Y. W. Pathway-based identification of a smoking associated 6-gene signature predictive of lung cancer risk and survival. Artificial Intelligence in Medicine . 10-2-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22326768
  • Wang, J., Xu, Y., Li, J., Sun, X., Wang, L. P., and Ji, W. Y. The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation in Laryngeal carcinoma. Oral Oncology . 6-2-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22317856
  • Zhang, Y., Sun, Y., Pan, Y., Li, C., Shen, L., Li, Y., Luo, X., Ye, T., Wang, R., Hu, H., Li, H., Wang, L., Pao, W., and Chen, H. Frequency of driver mutations in lung adenocarcinoma from female never-smokers varies with histological subtypes and age at diagnosis. Clinical Cancer Research . 8-2-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22317764

Research from 10 February 2012

  • Hall, F. S., Markou, A., Levin, E. D., and Uhl, G. R. Mouse models for studying genetic influences on factors determining smoking cessation success in humans. Annals of the New York Academy of Sciences 1248[1], 39-70. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22304675
  • Jang, J. H., Cotterchio, M., Borgida, A., Gallinger, S., and Cleary, S. P. Genetic Variants in Carcinogen Metabolizing Enzymes, Cigarette Smoking and Pancreatic Cancer Risk. Carcinogenesis . 2-2-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22301281
  • Kouidhi, S., Rouissi, K., Khedhiri, S., Ouerhani, S., Cherif, M., and Benammar-Elgaaied, A. MTHFR Gene Polymorphisms and Bladder Cancer Susceptibility: a Meta-Analysis Including Race, Smoking Status and Tumour Stage. Asian Pac.J.Cancer Prev. 12[9], 2227-2232. 2011. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22296361
  • Vanderweele, T. J., Asomaning, K., Tchetgen Tchetgen, E. J., Han, Y., Spitz, M. R., Shete, S., Wu, X., Gaborieau, V., Wang, Y., McLaughlin, J., Hung, R. J., Brennan, P., Amos, C. I., Christiani, D. C., and Lin, X. Genetic Variants on 15q25.1, Smoking, and Lung Cancer: An Assessment of Mediation and Interaction. American Journal of Epidemiology . 3-2-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22306564

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Research from 03 February 2012

  • Horimoto, A. R., Oliveira, C. M., Giolo, S. R., Soler, J. P., de, Andrade M., Krieger, J. E., and Pereira, A. C. Genetic analyses of smoking initiation, persistence, quantity, and age-at-onset of regular cigarette use in Brazilian families: the Baependi Heart Study. BMC.Med.Genet. 13[1], 9. 30-1-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22289947
  • Shyu, H. Y., Shieh, J. C., Lin, J. H., Wang, H. W., and Cheng, C. W. Polymorphisms of DNA Repair Pathway Genes and Cigarette Smoking in Relation to Susceptibility to Large Artery Atherosclerotic Stroke among Ethnic Chinese in Taiwan. J.Atheroscler.Thromb.  23-1-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22277767
  • Toll, L., Zaveri, N. T., Polgar, W. E., Jiang, F., Khroyan, T. V., Zhou, W., Xie, X. S., Stauber, G. B., Costello, M. R., and Leslie, F. M. AT-1001: A High Affinity and Selective alpha3beta4 Nicotinic Acetylcholine Receptor Antagonist Blocks Nicotine Self-Administration in Rats. Neuropsychopharmacology . 25-1-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22278092

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Research from 27 January 2012

  • Cents, R. A., Tiemeier, H., Velders, F. P., Jaddoe, V. W., Hofman, A., Verhulst, F. C., Lambregtse-van den Berg MP, and Hudziak, J. J. Maternal smoking during pregnancy and child emotional problems: The relevance of maternal and child 5-HTTLPR genotype. Am.J.Med.Genet.B Neuropsychiatr.Genet.  18-1-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22259195
  • Richter, G. M., Graetz, C., Pohler, P., Nothnagel, M., Dommisch, H., Laine, M. L., Folwaczny, M., Noack, B., Eickholz, P., Groessner-Schreiber, B., Jepsen, S., Loos, B. G., Schreiber, S., and Schaefer, A. S. Common genetic risk variants of TLR2 are not associated with periodontitis in large European case-control populations. Journal of Clinical Periodontology . 18-1-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22251071
  • Scoccianti, C., Vesin, A., Martel, G., Olivier, M., Brambilla, E., Timsit, J. F., Tavecchio, L., Brambilla, C., Field, J. K., and Hainaut, P. Prognostic value of TP53, KRAS and EGFR mutations in Non-Small Cell Lung Cancer: EUELC cohort. Eur.Respir.J.  20-1-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22267755

Research from 20 January 2012

  • Broms, U., Wedenoja, J., Largeau, M. R., Korhonen, T., Pitkaniemi, J., Keskitalo-Vuokko, K., Happola, A., Heikkila, K. H., Heikkila, K., Ripatti, S., Sarin, A. P., Salminen, O., Paunio, T., Pergadia, M. L., Madden, P. A., Kaprio, J., and Loukola, A. Analysis of Detailed Phenotype Profiles Reveals CHRNA5-CHRNA3-CHRNB4 Gene Cluster Association With Several Nicotine Dependence Traits. Nicotine Tob.Res.  12-1-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22241830
  • Dobrinas, M., Cornuz, J., Pedrido, L., and Eap, C. B. Influence of cytochrome P450 oxidoreductase genetic polymorphisms on CYP1A2 activity and inducibility by smoking. Pharmacogenet.Genomics 22[2], 143-151. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22246422
  • Ishikawa, M., Miyahara, R., Sonobe, M., Horiuchi, M., Mennju, T., Nakayama, E., Kobayashi, M., Kikuchi, R., Kitamura, J., Imamura, N., Huang, C. L., and Date, H. Higher expression of EphA2 and ephrin-A1 is related to favorable clinicopathological features in pathological stage I non-small cell lung carcinoma. Lung Cancer . 9-1-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22236865
  • Jasinska, A. J., Chua, H. F., Ho, S. S., Polk, T. A., Rozek, L. S., and Strecher, V. J. Amygdala response to smoking-cessation messages mediates the effects of serotonin transporter gene variation on quitting. Neuroimage.  2-1-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22245645
  • Kim, J., Cho, Y. A., Choi, I. J., Lee, Y. S., Kim, S. Y., Shin, A., Cho, S. J., Kook, M. C., Nam, J. H., Ryu, K. W., Lee, J. H., and Kim, Y. W. Effects of Interleukin-10 Polymorphisms, Helicobacter pylori Infection, and Smoking on the Risk of Noncardia Gastric Cancer. PLoS.One. 7[1], e29643. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22235320
  • Lockett, A. D., Van, Demark M., Gu, Y., Schweitzer, K. S., Sigua, N., Kamocki, K., Fijalkowska, I., Garrison, J., Fisher, A. J., Serban, K., Wise, R. A., Flotte, T. R., Mueller, C., Presson, R. G., Petrache, H. I., Tuder, R. M., and Petrache, I. Effect of cigarette smoke exposure and structural modifications on the alpha-1 antitrypsin interaction with caspases. Molecular Medicine . 10-1-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22245800
  • Monick, M. M., Beach, S. R., Plume, J., Sears, R., Gerrard, M., Brody, G. H., and Philibert, R. A. Coordinated changes in AHRR methylation in lymphoblasts and pulmonary macrophages from smokers. Am.J.Med.Genet.B Neuropsychiatr.Genet. 159B[2], 141-151. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22232023
  • Rudolph, A., Hein, R., Hoffmeister, M., Forsti, A., Hemminki, K., Risch, A., Brenner, H., and Chang-Claude, J. Copy number variations of GSTT1 and GSTM1, colorectal cancer risk and possible effect modification of cigarette smoking and menopausal hormone therapy. International Journal of Cancer . 10-1-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22234881

Research from 13 January 2012

  • Bousman, C. A., Rivard, C., Haese, J. D., Ambrosone, C., and Hyland, A. Alpha-5 and -3 nicotinic receptor gene variants predict nicotine dependence but not cessation: Findings from the COMMIT cohort. Am.J.Med.Genet.B Neuropsychiatr.Genet.  5-1-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22223462
  • Kiyohara, C., Washio, M., Horiuchi, T., Asami, T., Ide, S., Atsumi, T., Kobashi, G., Takahashi, H., and Tada, Y. Risk modification by CYP1A1 and GSTM1 polymorphisms in the association of cigarette smoking and systemic lupus erythematosus in a Japanese population. Scandinavian Journal of Rheumatology . 4-1-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22217397
  • Liu, T., Tyndale, R. F., David, S. P., Wang, H., Yu, X. Q., Chen, W., Wen, X. Z., and Chen, W. Q. Association between daily cigarette consumption and hypertension moderated by CYP2A6 genotypes in Chinese male current smokers. Journal of Human Hypertension . 5-1-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22217675
  • Quaak, M., Smerecnik, C., van Schooten, F. J., de, Vries H., and van Schayck, C. P. Knowledge, attitudes and preferences regarding genetic testing for smoking cessation. A cross-sectional survey among Dutch smokers. BMJ Open. 2, e000321. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22223839
  • Ren, J. H., He, W. S., Yan, G. L., Jin, M., Yang, K. Y., and Wu, G. EGFR mutations in non-small-cell lung cancer among smokers and non-smokers: A meta-analysis. Environmental and Molecular Mutagenesis 53[1], 78-82. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22223435
  • Scesnaite, A., Jarmalaite, S., Mutanen, P., Anttila, S., Nyberg, F., Benhamou, S., Boffetta, P., and Husgafvel-Pursiainen, K. Similar DNA methylation pattern in lung tumours from smokers and never-smokers with second-hand tobacco smoke exposure. Mutagenesis . 4-1-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22217548

Research from 06 January 2012

  • Haj, Mouhamed D., Ezzaher, A., Mechri, A., Neffati, F., Omezzine, A., Bouslama, A., Gaha, L., Douki, W., and Najjar, M. F. Effect of cigarette smoking on paraoxonase 1 activity according to PON1 L55M and PON1 Q192R gene polymorphisms. Environ.Health Prev.Med.  29-12-2011. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22205545
  • Huang, B., Liu, B., Yang, L., Li, Y., Cheng, M., Huang, D., Wang, H., Zhang, X., Zheng, J., Li, Q., Ji, W., Zhou, Y., and Lu, J. Functional genetic variants of c-Jun and their interaction with smoking and drinking increase the susceptibility to lung cancer in southern and eastern chinese. International Journal of Cancer . 20-12-2011. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22189957
  • Liu, Z., Sun, R., Lu, W., Dang, C., Song, Y., Wang, C., Zhang, X., Han, L., Cheng, H., Gao, W., Liu, J., and Lei, G. The -938A/A genotype of BCL2 gene is associated with esophageal cancer. Medical Oncology . 21-12-2011. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22187149
  • Murphy, S. K., Adigun, A., Huang, Z., Overcash, F., Wang, F., Jirtle, R. L., Schildkraut, J. S., Murtha, A. P., Iversen, E. S., and Hoyo, C. Gender-specific methylation differences in relation to prenatal exposure to cigarette smoke. Gene . 20-12-2011. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22202639
  • Tekpli, X., Zienolddiny, S., Skaug, V., Stangeland, L., Haugen, A., and Mollerup, S. DNA methylation of the CYP1A1 enhancer is associated with smoking-induced genetic alterations in human lung. International Journal of Cancer . 31-12-2011. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22213191

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