Nicotine 2012

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Research from 18 May 2012

  • Goniewicz, M. L., Koszowski, B., Czogala, J., Kuma, T., Gawron, M., Kosmider, L., Knysak, J., and Sobczak, A. Variations in nicotine yields between single cigarettes. Central European Journal of Public Health 20[1], 58-61. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22571019
  • Kim, Y. S., Shin, S. I., Kang, K. L., Chung, J. H., Herr, Y., Bae, W. J., and Kim, E. C. Nicotine and lipopolysaccharide stimulate the production of MMPs and prostaglandin E(2) by hypoxia-inducible factor-1alpha up-regulation in human periodontal ligament cells*. Journal of Periodontal Research . 9-5-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22571166
  • Myers, C. S., Taylor, R. C., Salmeron, B. J., Waters, A. J., and Heishman, S. J. Nicotine Enhances Alerting, but not Executive, Attention in Smokers and Nonsmokers. Nicotine.Tob.Res.  9-5-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22573728

Research from 11 May 2012

  • Cohen, A., Koob, G. F., and George, O. Robust Escalation of Nicotine Intake with Extended Access to Nicotine Self-Administration and Intermittent Periods of Abstinence. Neuropsychopharmacology . 2-5-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22549121
  • Perez, X., Ly, J., McIntosh, J. M., and Quik, M. Chronic Nicotine Exposure Depresses Dopamine Release in Nonhuman Primate Nucleus Accumbens. Journal of Pharmacology and Experimental Therapeutics . 4-5-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22562772
  • Wang, S., Zhang, C., Zhang, M., Liang, B., Zhu, H., Lee, J., Viollet, B., Xia, L., Zhang, Y., and Zou, M. H. Activation of AMP-activated protein kinase alpha2 by nicotine instigates formation of abdominal aortic aneurysms in mice in vivo. Nature Medicine . 6-5-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22561688
  • Wongtrakool, C., Grooms, K., Ping, X. D., Rivera, H., Ward, J., Roser-Page, S., Roman, J., Brown, L. A., and Gauthier, T. W. In Utero Nicotine Exposure Promotes M2 Activation in Neonatal Mice Alveolar Macrophages. Pediatric Research . 4-5-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22562289

Research from 27 April 2012

  • Cucina, A., Dinicola, S., Coluccia, P., Proietti, S., D'Anselmi, F., Pasqualato, A., and Bizzarri, M. Nicotine stimulates proliferation and inhibits apoptosis in colon cancer cell lines through activation of survival pathways. Journal of Surgical Research . 10-3-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22520577
  • Galitovskiy, V., Chernyavsky, A. I., Edwards, R. A., and Grando, S. A. Muscle sarcomas and alopecia in A/J mice chronically treated with nicotine. Life Sciences . 12-4-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22521759
  • Li, Z. Z. and Dai, Q. Y. Pathogenesis of abdominal aortic aneurysms: role of nicotine and nicotinic acetylcholine receptors. Mediators.Inflamm. 2012, 103120. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22529515
  • Umezu, T. Unusual effects of nicotine as a psychostimulant on ambulatory activity in mice. ISRN.Pharmacol. 2012, 170981. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22530136
  • Zarrelli, A., Dellagreca, M., Parolisi, A., Iesce, M. R., Cermola, F., Temussi, F., Isidori, M., Lavorgna, M., Passananti, M., and Previtera, L. Chemical fate and genotoxic risk associated with hypochlorite treatment of nicotine. Science of the Total Environment . 18-4-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22521104

Research from 20 April 2012

  • Domino, E. F., Ni, L., Domino, J. S., Yang, W., Evans, C., Guthrie, S., Wang, H., Koeppe, R. A., and Zubieta, J. K. Denicotinized Versus Average Nicotine Tobacco Cigarette Smoking Differentially Releases Striatal Dopamine. Nicotine Tob.Res.  5-4-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22491891
  • Ebben, M. R. and Krieger, A. C. Narcolepsy with cataplexy masked by the use of nicotine. J.Clin.Sleep Med. 8[2], 195-196. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22505866
  • Lee, W., Ray, R., Bergen, A. W., Swan, G. E., Thomas, P., Tyndale, R. F., Benowitz, N. L., Lerman, C., and Conti, D. V. DRD1 associations with smoking abstinence across slow and normal nicotine metabolizers. Pharmacogenet.Genomics . 8-4-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22495174
  • Rothig, A., Schreckenberg, R., Weber, K., Conzelmann, C., da Costa Rebelo, R. M., and Schluter, K. D. Effects of Nicotine on PTHrP and PTHrP Receptor Expression in Rat Coronary Endothelial Cells. Cell Physiol Biochem. 29[3-4], 485-492. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22508055
  • Sun, L. C., Lin, J. T., Li, W., Zhang, L., Zhou, T. L., and Zhang, X. Y. Nicotininhibits histone deacetylase 6 activity and chaperone-dependent activation of the glucocorticoid receptor in A549 cells. Chin Med.J.(Engl.) 125[4], 662-666. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22490492

Research from 13 April 2012

  • Cao, J., Gautier, N. M., and Li, M. D. CD-1 mice Show Individual Differences in Nicotine Preference in a Modified Two-Bottle Oral Self-Administration Model. Front Psychiatry 3, 28. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22479254
  • Weaver, M. T., Geier, C. F., Levin, M. E., Caggiula, A. R., Sved, A. F., and Donny, E. C. Adolescent exposure to nicotine results in reinforcement enhancement but does not affect adult responding in rats. Drug and Alcohol Dependence . 6-4-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22483812

Research from 05 April 2012

  • Barrett, S. P. and Darredeau, C. The acute effects of nicotine on the subjective and behavioural responses to denicotinized tobacco in dependent smokers. Behavioural Pharmacology . 30-3-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22470104

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Research from 30 March 2012

  • Budulac, S. E., Vonk, J. M., Postma, D. S., Siedlinski, M., Timens, W., and Boezen, M. H. Nicotinic Acetylcholine Receptor Variants Are Related to Smoking Habits, but Not Directly to COPD. PLoS.One. 7[3], e33386. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22438921
  • Cunningham, C. S., Javors, M., and McMahon, L. R. Pharmacologic characterization of a nicotine discriminative stimulus in rhesus monkeys. Journal of Pharmacology and Experimental Therapeutics . 21-3-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/2243847
  • Panlilio, L. V., Justinova, Z., Mascia, P., Pistis, M., Luchicchi, A., Lecca, S., Barnes, C., Redhi, G. H., Adair, J., Heishman, S. J., Yasar, S., Aliczki, M., Haller, J., and Goldberg, S. R. Novel Use of a Lipid-Lowering Fibrate Medication to Prevent Nicotine Reward and Relapse: Preclinical Findings. Neuropsychopharmacology . 28-3-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22453137
  • van der Zanden, E. P., Hilbers, F. W., Verseijden, C., van den Wijngaard, R. M., Skynner, M., Lee, K., Ulloa, L., Boeckxstaens, G. E., and de Jonge, W. J. Nicotinic acetylcholine receptor expression and susceptibility to cholinergic immunomodulation in human monocytes of smoking individuals. Neuroimmunomodulation. 19[4], 255-265. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22441542

Research from 23 March 2012

  • Fisher, D. J., Grant, B., Smith, D. M., Borracci, G., Labelle, A., and Knott, V. J. Nicotine and the hallucinating brain: Effects on mismatch negativity (MMN) in schizophrenia. Psychiatry Research . 15-3-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22425471
  • Goeders, N. E., Cohen, A., Fox, B. S., Azar, M. R., George, O., and Koob, G. F. Effects of the combination of metyrapone and oxazepam on intravenous nicotine self-administration in rats. Psychopharmacology (Berl) . 15-3-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22418732
  • Rose, J. E., Dehkordi, O., Fatemi, M., Raghupathi, R., Millis, R. M., and Jayam-Trouth, A. Neuroanatomical evidence for a putative autocrine/paracrine signaling system involving nicotinic acetylcholine receptors, purinergic receptors, and nitric oxide synthase in the airways. Journal of Neuroscience Research 90[4], 849-859. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22420037

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Research from 09 March 2012

  • Baek, O., Zhu, W., Kim, H. C., and Lee, S. W. Effects of nicotine on the growth and protein expression of Porphyromonas gingivalis. J.Microbiol. 50[1], 143-148. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22367949
  • Caldwell, B., Sumner, W., and Crane, J. A Systematic Review of Nicotine by Inhalation: Is There a Role for the Inhaled Route? Nicotine Tob.Res.  29-2-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22377934
  • Kim, S. Y., Kang, K. L., Lee, J. C., and Heo, J. S. Nicotinic acetylcholine receptor alpha7 and beta4 subunits contribute nicotine-induced apoptosis in periodontal ligament stem cells. Molecules and Cells . 29-2-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22382680
  • Parrott, A. C. and Murphy, R. S. Explaining the stress-inducing effects of nicotine to cigarette smokers. Hum.Psychopharmacol. 27[2], 150-155. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22389079

Research from 02 March 2012

  • Benowitz, N. L., Dains, K. M., Hall, S., Stewart, S. L., Wilson, M., Dempsey, D., and Jacob, P., III. Smoking Behavior and Exposure to Tobacco Toxicants During 6 months of Smoking Progressively Reduced Nicotine Content Cigarettes. Cancer Epidemiology, Biomarkers and Prevention . 21-2-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22354905
  • Raupach, T., Hoogsteder, P. H., and Onno van Schayck, C. P. Nicotine vaccines to assist with smoking cessation: current status of research. Drugs 72[4], e1-e16. 5-3-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22356293

Research from 17 February 2012

  • Abobo, C. V., Ma, J., and Liang, D. Effect of Menthol on Nicotine Pharmacokinetics in Rats After Cigarette Smoke Inhalation. Nicotine Tob.Res.  6-2-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22311961
  • Cao, Y. A., Featherstone, R. E., Gandal, M. J., Liang, Y., Jutzeler, C., Saunders, J., Tatard-Leitman, V., Chen, J., Weinberger, D. R., Lerman, C., and Siegel, S. J. Nicotine normalizes event related potentials in COMT-Val-tg mice and increases gamma and theta spectral density. Behavioral Neuroscience . 6-2-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22309446
  • Govind, A. P., Walsh, H., and Green, W. N. Nicotine-induced upregulation of native neuronal nicotinic receptors is caused by multiple mechanisms. Journal of Neuroscience 32[6], 2227-2238. 8-2-2012.Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22323734
  • Martinez de Morentin, P. B., Whittle, A. J., Ferno, J., Nogueiras, R., Dieguez, C., Vidal-Puig, A., and Lopez, M. Nicotine Induces Negative Energy Balance Through Hypothalamic AMP-Activated Protein Kinase. Diabetes . 7-2-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22315316

Research from 10 February 2012

  • Johnson, J. E., Slade, S., Wells, C., Petro, A., Sexton, H., Rezvani, A. H., Brown, M. L., Paige, M. A., McDowell, B. E., Xiao, Y., Kellar, K. J., and Levin, E. D. Assessing the effects of chronic sazetidine-A delivery on nicotine self-administration in both male and female rats. Psychopharmacology (Berl) . 2-2-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22297831
  • Pillai, S. and Chellappan, S. proportional, variant7 nicotinic acetylcholine receptor subunit in Angiogenesis and Epithelial To Mesenchymal Transition. Curr.Drug Targets.  17-1-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22300034

Research from 03 February 2012

  • Ashford, K. and Westneat, S. Prenatal hair nicotine analysis in homes with multiple smokers. Nursing Clinics of North America 47[1], 13-20. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22289394

Research from 27 January 2012

  • Bawazeer, S., Watson, D. G., and Knottenbelt, C. Determination of nicotine exposure in dogs subjected to passive smoking using methanol extraction of hair followed by hydrophilic interaction chromatography in combination with Fourier transform mass spectrometry. Talanta 88, 408-411. 15-1-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22265518
  • Nishimura, H., Furumiya, J., Nakanishi, A., and Hashimoto, Y. [Implications of nicotine detected in autopsy cases of newborn babies and infants from the perspective of social medicine]. Nihon Arukoru Yakubutsu Igakkai Zasshi 46[5], 446-453. 2011. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22256593

Research from 20 January 2012

  • Alamanda, V., Singh, S., Lawrence, N. J., and Chellappan, S. P. Nicotine-mediated induction of E-selectin in aortic endothelial cells requires Src kinase and E2F1 transcriptional activity. Biochemical and Biophysical Research Communications . 3-1-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22240023
  • Colosimo, C. and Inghilleri, M. A further case of nicotine sensitivity in multiple system atrophy. Clinical Neuropharmacology 35[1], 51-52. 2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22240862
  • Fahim, R. E., Kessler, P. D., Fuller, S. A., and Kalnik, M. W. Nicotine Vaccines. CNS.Neurol.Disord.Drug Targets.  10-1-2012. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22229310
  • Lobina, C., Carai, M. A., Froestl, W., Mugnaini, C., Pasquini, S., Corelli, F., Gessa, G. L., and Colombo, G. Activation of the GABA(B) Receptor Prevents Nicotine-Induced Locomotor Stimulation in Mice. Front Psychiatry 2, 76. 2011. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22232609
  • Schnoll, R. A., Wileyto, E. P., and Lerman, C. Extended duration therapy with transdermal nicotine may attenuate weight gain following smoking cessation. Addictive Behaviors . 26-12-2011. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22244706

Research from 06 January 2012

  • Brown, K. C., Lau, J. K., Dom, A. M., Witte, T. R., Luo, H., Crabtree, C. M., Shah, Y. H., Shiflett, B. S., Marcelo, A. J., Proper, N. A., Hardman, W. E., Egleton, R. D., Chen, Y. C., Mangiarua, E. I., and Dasgupta, P. MG624, an alpha7-nAChR antagonist, inhibits angiogenesis via the Egr-1/FGF2 pathway. Angiogenesis.  25-12-2011. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22198237
  • Ji, X., Wang, A., Trandafir, C. C., and Kurahashi, K. Influence of Experimental Subarachnoid Hemorrhage on Nicotine-induced Contraction of the Rat Basilar Artery in Relation to Arachidonic Acid Metabolites Signaling Pathway. J.Stroke Cerebrovasc.Dis.  29-12-2011. Abstract or full text available at: http://www.ncbi.nlm.nih.gov/pubmed/22209310

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